Why PlasmaDerm is unique

PlasmaDerm is a direct cold plasma procedure. It generates the cold plasma directly on the wound surface – the body thus becomes part of the physical process. The high-frequency electric field generated during this process can also have an effect on the body and demonstrably improve microcirculation even in deep tissue layers.

Proven deep-acting microcirculation

Unique to PlasmaDerm: Microcirculation is demonstrably increased even in deep tissue layers – an important advantage for PlasmaDerm.

Reduction of bacterial load

Cold plasma inactivates even multi-resistant germs and has a positive effect on the wound environment.

Influence on inflammatory processes

Regular use of the cold plasma therapy device helps to overcome the chronic inflammatory phase.

Promoting wound healing

The combination of germ reduction, soothed inflammation and improved microcirculation creates optimal conditions for tissue regeneration and can simultaneously reduce itching, pain and wound odor.

Level of action 1

Demonstrably improved microcirculation

For active wound healing, tissue needs sufficient oxygen and nutrients. In many chronic wounds, microcirculation is restricted; the tissue appears pale, cool, and poorly perfused. PlasmaDerm not only affects the wound surface but also works deep into the tissue via an electric field, improving local blood flow.

How PlasmaDerm specifically stimulates microcirculation

Chronic or poorly healing wounds are often accompanied by impaired microcirculation. PlasmaDerm activates two mechanisms in this regard: In the short term and superficially, the reactive species of the cold plasma stimulate the production of the body's own nitric oxide (NO). NO relaxes the smooth muscle of blood vessels, dilates capillaries, and immediately increases blood flow. In the long term, the high-frequency electric field acts by influencing the nervous regulation of blood vessels and sustainably increasing microcirculation even in deeper tissue layers.

Why increased microcirculation is crucial for healing

The combined effect of NO-induced vasodilation and deep perfusion enhancement improves oxygen transport, nutrient supply, and the removal of metabolic waste products. This provides the tissue with the necessary conditions for essential healing processes such as cell division, cell migration, tissue regeneration, and angiogenesis. In this way, stagnant wounds can return to an active regeneration phase

Level of action 2

Germ reduction, antimicrobial effect

A high bacterial load is considered one of the most significant factors impairing wound healing. Bacteria promote inflammation, delay regeneration, and increase the risk of infection. PlasmaDerm leads to an immediate and significant reduction in bacterial load, including multi-resistant pathogens, which are effectively inactivated.

How cold plasma attacks germs directly at the surface

Reactive oxygen and nitrogen species from the cold-generated plasma interact with the wound surface and with the water in the wound exudate and tissue. This results in a rapid reduction of the pH value in the wound environment by one to two log units. Additionally, the reactive species act directly on the proteins and enzyme systems of the pathogens. These rapid, multimodal changes are responsible for the antimicrobial effect.

Less infection pressure,less irritation

By reducing pathogenic germs, PlasmaDerm promotes a more favorable environment for wound healing. Pressure on the wound tissue decreases, and the wound environment becomes calmer. Fewer germs help inflammatory processes subside. Potential side effects such as odor or increased itching can be reduced.

Level of action 3

Support for chronic inflammation

Chronic wounds often remain in a persistent inflammatory phase – with typical accompanying symptoms such as redness, swelling, pain, and significantly slowed regeneration. PlasmaDerm can provide impulses that modulate these overactive processes and thus support more favorable conditions for regenerative processes.

Calms inflammatory processes

Cold plasma can modulate the activity of pro-inflammatory messenger substances (cytokines) and thus support the balance between defense mechanisms and regenerative processes in the wound.

Inflammation modulation as a basis for tissue regeneration

A modulated inflammatory activity facilitates the tissue's transition to the next healing phase. This allows entrenched, long-standing wounds to become more responsive and better react to further therapy.

Level of action 4

Promoting wound healing

PlasmaDerm promotes wound healing and tissue regeneration through the interaction of the generated reactive species and the electric field. The reactive species stimulate the body's own signaling pathways and activate cells involved in wound healing—including fibroblasts and keratinocytes. This supports cell proliferation, cell migration, and collagen formation. Additionally, the reactive species stimulate the formation of new blood vessels and contribute to the reduction of excessive inflammation, thereby increasing the cells' resilience to oxidative stress.

The electric field enhances key processes of wound healing.

The electric field enhances these effects by increasing microcirculation into deep tissue layers and supporting the activity of connective tissue cells.

Positive effect on itching, wound pain and wound odor

Cold plasma can soothe the wound environment, modulate inflammatory processes, and reduce pathogenic germs. This makes the wound less irritated, which can potentially alleviate itching and wound pain. At the same time, the reduced germ load can minimize the development of unpleasant odors.

Experience cold plasma in practice – test it now without obligation

Receive a personal introduction to the cold plasma therapy device to learn about its operating principle, processes, and integration into your structures

Contact